data_2542 #Corrected using PDB structure: 1WQQ_ # #N.B. (Observed* = Observed shift + Offset correction) # #After reference correction, the following residues still #have a N chemical shift difference (obs*-pred) greater than 10.0ppm: #NUM AA CS Observed* Predicted #112 W N 114.78 126.91 # #The average CS difference between predicted and observed: #HA CA CB CO N HN #N/A N/A N/A N/A -2.32 N/A # #bmr2542.str.corr chemical shifts have been re-referenced with the following #offsets (these values have been added to the original bmr2542.str file): #HA CA CB CO N HN #N/A N/A N/A N/A -2.32 N/A # #The 95% confidence intervals for the above recommended offsets are: # HA CA CB CO N HN # N/A N/A N/A N/A +/-0.37 N/A # #The Correlation Coefficients between predicted and observed #chemical shifts are: #HA CA CB CO N HN #N/A N/A N/A N/A 0.856 N/A # #The RMSD between predicted and observed* (reference #corrected) chemical shifts are: #HA CA CB CO N HN #N/A N/A N/A N/A 2.099 N/A # ####################### # Entry information # ####################### save_entry_information _Saveframe_category entry_information _Entry_title ; 1H and 15N NMR Study of Human Lysozyme ; loop_ _Author_ordinal _Author_family_name _Author_given_name _Author_middle_initials _Author_family_title 1 Ohkubo Tadayasu . . 2 Taniyama Yoshio . . 3 Kikuchi Masakazu . . stop_ _BMRB_accession_number 2542 _BMRB_flat_file_name bmr2542.str _Entry_type revision _Submission_date 1995-07-31 _Accession_date 1996-04-13 _Entry_origination BMRB _NMR_STAR_version 2.1 _Experimental_method NMR loop_ _Saveframe_category_type _Saveframe_category_type_count assigned_chemical_shifts 1 stop_ loop_ _Data_type _Data_type_count '15N chemical shifts' 148 stop_ loop_ _Revision_date _Revision_keyword _Revision_author _Revision_detail 1999-06-14 revision BMRB 'Converted to BMRB NMR-STAR V 2.1 format' 1996-04-13 revision BMRB 'Link to the Protein Data Bank added' 1996-03-25 reformat BMRB 'Converted to the BMRB 1996-03-01 STAR flat-file format' 1995-07-31 original BMRB 'Last release in original BMRB flat-file format' stop_ save_ ############################# # Citation for this entry # ############################# save_entry_citation _Saveframe_category entry_citation _Citation_full ; Ohkubo, Tadayasu, Taniyama, Yoshio, Kikuchi, Masakazu, "1H and 15N NMR Study of Human Lysozyme," J. Biochem. 110 (6), 1022-1029 (1991). ; _Citation_title ; 1H and 15N NMR Study of Human Lysozyme ; _Citation_status published _Citation_type journal _MEDLINE_UI_code ? loop_ _Author_ordinal _Author_family_name _Author_given_name _Author_middle_initials _Author_family_title 1 Ohkubo Tadayasu . . 2 Taniyama Yoshio . . 3 Kikuchi Masakazu . . stop_ _Journal_abbreviation 'J. Biochem.' _Journal_volume 110 _Journal_issue 6 _Page_first 1022 _Page_last 1029 _Year 1991 save_ ################################## # Molecular system description # ################################## save_system_lysozyme _Saveframe_category molecular_system _Mol_system_name lysozyme _Abbreviation_common ? loop_ _Mol_system_component_name _Mol_label lysozyme $lysozyme stop_ _System_physical_state ? _System_oligomer_state ? _System_paramagnetic ? loop_ _Database_name _Database_accession_code _Database_entry_mol_name _Database_entry_details PDB 1C43 "A Chain A, Mutant Human Lysozyme With Foreign N-Terminal Residues" . PDB 1C45 "A Chain A, Mutant Human Lysozyme With Foreign N-Terminal Residues" . PDB 1OUF "Contribution Of Hydrophobic Residues To The Stability Of Human Lysozyme: X-Ray Structure Of The V130a Mutant" . PDB 1RE2 "A Chain A, Human Lysozyme Labelled With Two 2',3'-Epoxypropyl Beta- Glycoside Of N-Acetyllactosamine" . PDB 1REM "Human Lysozyme With Man-B1,4-Glcnac Covalently Attached To Asp53" . PDB 1REY "Human Lysozyme-N,N'-Diacetylchitobiose Complex" . PDB 1REZ "Human Lysozyme-N-Acetyllactosamine Complex" . PDB 1LZS "A Chain A, Lysozyme (Lz604) (E.C.3.2.1.17) Complexed With N-Acetylchitose Oligomers" . PDB 1C7P "A Chain A, Crystal Structure Of Mutant Human Lysozyme With Four Extra Residues (Eaea) At The N-Terminal" . PDB 1C46 "A Chain A, Mutant Human Lysozyme With Foreign N-Terminal Residues" . PDB 1JSF "Full-Matrix Least-Squares Refinement Of Human Lysozyme" . PDB 1REX "Native Human Lysozyme" . PDB 1LZ1 "Lysozyme (E.C.3.2.1.17)" . PDB 1LZR "Lysozyme (Lz406) (E.C.3.2.1.17) Complexed With Tetra-Acetyl-Chitotetraose" . PDB 2HEA "Contribution Of Water Molecules In The Interior Of A Protein To The Conformational Stability" . PDB 1JKC "Human Lysozyme Mutant With Trp 109 Replaced By Phe" . PDB 2HEB "Contribution Of Water Molecules In The Interior Of A Protein To The Conformational Stability" . PDB 1LHL "Lysozyme (E.C.3.2.1.17) Mutant With Ala 47 Replaced By Proline (A47p)" . PDB 134L "Lysozyme (E.C.3.2.1.17) Mutant With Arg 115 Replaced By Glu (R115e)" . PDB 133L "Lysozyme (E.C.3.2.1.17) Mutant With Arg 115 Replaced By His (R115h)" . PDB 1OUA "Contribution Of Hydrophobic Residues To The Stability Of Human Lysozyme: X-Ray Structure Of The I56t Mutant" . PDB 1LOZ "Amyloidogenic Variant (I56t) Variant Of Human Lysozyme" . PDB 1TDY "Lysozyme (E.C.3.2.1.17) Mutant With Tyr 63 Replaced By Trp (Y63W)" . PDB 1GF8 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GE3 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At Left-Handed Helical Positions" . PDB 1GE1 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At Left-Handed Helical Positions" . PDB 1GDX "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At Left-Handed Helical Positions" . PDB 1B7S "Verification Of Spmp Using Mutant Human Lysozymes" . PDB 2MEG "Changes In Conformational Stability Of A Series Of Mutant Human Lysozymes At Constant Positions" . PDB 1JKB "Human Lysozyme Mutant With Glu 35 Replaced By Ala" . PDB 1GE0 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At Left-Handed Helical Positions" . PDB 1CKG "A Chain A, T52v Mutant Human Lysozyme" . PDB 1CKH "A Chain A, T70v Mutant Human Lysozyme" . PDB 1CKF "A Chain A, T52a Mutant Human Lysozyme" . PDB 1CKD "A Chain A, T43v Mutant Human Lysozyme" . PDB 1CKC "A Chain A, T43a Mutant Human Lysozyme" . PDB 1CJ9 "A Chain A, T40v Mutant Human Lysozyme" . PDB 1CJ8 "A Chain A, T40a Mutant Human Lysozyme" . PDB 1CJ7 "A Chain A, T11v Mutant Human Lysozyme" . PDB 1CJ6 "A Chain A, T11a Mutant Human Lysozyme" . PDB 1BB5 "A Chain A, Human Lysozyme Mutant A96l Complexed With Chitotriose" . PDB 1BB3 "A Chain A, Human Lysozyme Mutant A96l" . PDB 2MEI "Contribution Of Hydrophobic Effect To The Conformational Stability Of Human Lysozyme" . PDB 2MEH "Contribution Of Hydrophobic Effect To The Conformational Stability Of Human Lysozyme" . PDB 2HEF "Contribution Of Water Molecules In The Interior Of A Protein To The Conformational Stability" . PDB 2HED "Contribution Of Water Molecules In The Interior Of A Protein To The Conformational Stability" . PDB 2HEC "Contribution Of Water Molecules In The Interior Of A Protein To The Conformational Stability" . PDB 1LHK "Lysozyme (E.C.3.2.1.17) Mutant With Asp 91 Replaced By Pro (D91p)" . PDB 1GE4 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At Left-Handed Helical Positions" . PDB 1B7O "A Chain A, Verification Of Spmp Using Mutant Human Lysozymes" . PDB 1B7N "A Chain A, Verification Of Spmp Using Mutant Human Lysozymes" . PDB 2HEE "Contribution Of Water Molecules In The Interior Of A Protein To The Conformational Stability" . PDB 1TBY "Lysozyme (E.C.3.2.1.17) Mutant With Tyr 63 Replaced By Leu (Y63L)" . PDB 1D6P "A Chain A, Human Lysozyme L63 Mutant Labelled With 2',3'-Epoxypropyl N, N'-Diacetylchitobiose" . PDB 1B7Q "A Chain A, Verification Of Spmp Using Mutant Human Lysozymes" . PDB 1LHJ "Lysozyme (E.C.3.2.1.17) Mutant With Pro 103 Replaced By Gly (P103g)" . PDB 1LHI "Lysozyme (E.C.3.2.1.17) Mutant With Pro 71 Replaced By Gly (P71g)" . PDB 207L "A Chain A, Mutant Human Lysozyme C77a" . PDB 1HNL "Lysozyme (E.C.3.2.1.17) Mutant With Cys 77 Replaced By Ala (C77a) Complexed With Glutathione" . PDB 208L "A Chain A, Mutant Human Lysozyme C77a" . PDB 1LZ4 "Lysozyme (E.C.3.2.1.17) Mutant With Cys 77 Replaced By Ala (C77a)" . PDB 1TAY "Lysozyme (E.C.3.2.1.17) Mutant With Tyr 63 Replaced By Ala (Y63A)" . PDB 1GE2 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At Left-Handed Helical Positions" . PDB 1B7P "A Chain A, Verification Of Spmp Using Mutant Human Lysozymes" . PDB 1LHH "Lysozyme (E.C.3.2.1.17) Mutant With Val 110 Replaced By Pro (V110p)" . PDB 1INU "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GFK "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GFJ "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GFG "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GFE "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GFA "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GFV "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GFU "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GFR "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GDW "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At Left-Handed Helical Positions" . PDB 1GBO "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GB5 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GAY "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1B7R "A Chain A, Verification Of Spmp Using Mutant Human Lysozymes" . PDB 1DI3 "A Chain A, Role Of Amino Acid Residues At Turns In The Conformational Stability And Folding Of Human Lysozyme" . PDB 1LYY "Amyloidogenic Variant (Asp67his) Of Human Lysozyme" . PDB 2MED "Contribution Of Hydrophobic Effect To The Conformational Stability Of Human Lysozyme" . PDB 1D6Q "A Chain A, Human Lysozyme E102 Mutant Labelled With 2',3'-Epoxypropyl Glycoside Of N-Acetyllactosamine" . PDB 1JKA "Human Lysozyme Mutant With Glu 35 Replaced By Asp" . PDB 2MEC "A Chain A, Changes In Conformational Stability Of A Series Of Mutant Human Lysozymes At Constant Positions" . PDB 2MEF "Contribution Of Hydrophobic Effect To The Conformational Stability Of Human Lysozyme" . PDB 1B5Z "A Chain A, Contribution Of Hydrogen Bonds To The Conformational Stability Of Human Lysozyme: Calorimetry And X-Ray Analysis Of Six Ser->ala Mutants" . PDB 1B5X "A Chain A, Contribution Of Hydrogen Bonds To The Conformational Stability Of Human Lysozyme: Calorimetry And X-Ray Analysis Of Six Ser->ala Mutants" . PDB 1B5U "A Chain A, Contribution Of Hydrogen Bonds To The Conformational Stability Of Human Lysozyme: Calorimetry And X-Ray Analysis Of Six Ser->ala Mutant" . PDB 1B5V "A Chain A, Contribution Of Hydrogen Bonds To The Conformational Stability Of Human Lysozyme: Calorimetry And X-Ray Analysis Of Six Ser->ala Mutants" . PDB 1B5W "A Chain A, Contribution Of Hydrogen Bonds To The Conformational Stability Of Human Lysozyme: Calorimetry And X-Ray Analysis Of Six Ser->ala Mutants" . PDB 1B5Y "A Chain A, Contribution Of Hydrogen Bonds To The Conformational Stability Of Human Lysozyme: Calorimetry And X-Ray Analysis Of Six Ser->ala Mutants" . PDB 1EQ4 "A Chain A, Crystal Structures Of Salt Bridge Mutants Of Human Lysozyme" . PDB 1GB0 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GB7 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GB8 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GBX "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GBY "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GB2 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 2MEB "Changes In Conformational Stability Of A Series Of Mutant Human Lysozymes At Constant Positions" . PDB 2MEE "Contribution Of Hydrophobic Effect To The Conformational Stability Of Human Lysozyme" . PDB 1YAM "Mol_id: 1; Molecule: Lysozyme; Chain: Null; Ec: 3.2.1.17; Engineered: Yes; Mutation: I106v" . PDB 1YAN "Mol_id: 1; Molecule: Lysozyme; Chain: Null; Ec: 3.2.1.17; Engineered: Yes; Mutation: I23v" . PDB 1YAO "Mol_id: 1; Molecule: Lysozyme; Chain: Null; Ec: 3.2.1.17; Engineered: Yes; Mutation: I56v" . PDB 1YAP "Mol_id: 1; Molecule: Lysozyme; Chain: Null; Ec: 3.2.1.17; Engineered: Yes; Mutation: I59v" . PDB 1YAQ "Mol_id: 1; Molecule: Lysozyme; Chain: Null; Ec: 3.2.1.17; Engineered: Yes; Mutation: I89v" . PDB 1GAZ "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GB6 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GBW "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1B7L "A Chain A, Verification Of Spmp Using Mutant Human Lysozymes" . PDB 1B7M "A Chain A, Verification Of Spmp Using Mutant Human Lysozymes" . PDB 1EQ5 "A Chain A, Crystal Structures Of Salt Bridge Mutants Of Human Lysozyme" . PDB 1EQE "A Chain A, Crystal Structures Of Salt Bridge Mutants Of Human Lysozyme" . PDB 1GB3 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GB9 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GBZ "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GFT "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GF9 "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1GFH "A Chain A, Crystal Structure Of Mutant Human Lysozyme Substituted At The Surface Positions" . PDB 1LAA "Lysozyme (E.C.3.2.1.17) Mutant With Asp 53 Replaced By Glu (D53E)" . PDB 1WQR "Contribution Of Hydrogen Bonds To The Conformational Stability Of Human Lysozyme" . PDB 1TCY "Lysozyme (E.C.3.2.1.17) Mutant With Tyr 63 Replaced By Phe (Y63F)" . PDB 1OUB "Contribution Of Hydrophobic Residues To The Stability Of Human Lysozyme: X-Ray Structure Of The V100a Mutant" . PDB 1OUC "Contribution Of Hydrophobic Residues To The Stability Of Human Lysozyme: X-Ray Structure Of The V110a Mutant" . PDB 1OUD "Contribution Of Hydrophobic Residues To The Stability Of Human Lysozyme: X-Ray Structure Of The V121a Mutant" . PDB 1OUE "Contribution Of Hydrophobic Residues To The Stability Of Human Lysozyme: X-Ray Structure Of The V125a Mutant" . PDB 1OUG "Contribution Of Hydrophobic Residues To The Stability Of Human Lysozyme: X-Ray Structure Of The V2a Mutant" . PDB 1OUH "Contribution Of Hydrophobic Residues To The Stability Of Human Lysozyme: X-Ray Structure Of The V74a Mutant" . PDB 1OUI "Contribution Of Hydrophobic Residues To The Stability Of Human Lysozyme: X-Ray Structure Of The V93a Mutant" . PDB 1OUJ "Contribution Of Hydrophobic Residues To The Stability Of Human Lysozyme: X-Ray Structure Of The V99a Mutant" . PDB 1WQM "Contribution Of Hydrogen Bonds To The Conformational Stability Of Human Lysozyme" . PDB 1WQN "Contribution Of Hydrogen Bonds To The Conformational Stability Of Human Lysozyme" . PDB 1WQO "Contribution Of Hydrogen Bonds To The Conformational Stability Of Human Lysozyme" . PDB 1WQP "Contribution Of Hydrogen Bonds To The Conformational Stability Of Human Lysozyme" . PDB 1WQQ "Contribution Of Hydrogen Bonds To The Conformational Stability Of Human Lysozyme" . PDB 2MEA "A Chain A, Changes In Conformational Stability Of A Series Of Mutant Human Lysozymes At Constant Positions" . PDB 2LHM "Lysozyme (E.C.3.2.1.17) (Apo) (Mutant With Gln 86 Replaced B Asp And Ala 92 Replaced By Asp) (Q86D,A92D)" . PDB 3LHM "Lysozyme (E.C.3.2.1.17) (Holo) (Mutant With Gln 86 Replaced By Asp And Ala 92 Replaced By Asp) (Q86D,A92D)" . stop_ save_ ######################## # Monomeric polymers # ######################## save_lysozyme _Saveframe_category monomeric_polymer _Mol_type polymer _Mol_polymer_class protein _Name_common lysozyme _Abbreviation_common ? _Enzyme_commission_number 3.2.1.17 ############################## # Polymer residue sequence # ############################## _Residue_count 130 _Mol_residue_sequence ; KVFERCELARTLKRLGMDGY RGISLANWMCLAKWESGYNT RATNYNAGDRSTDYGIFQIN SRYWCNDGKTPGAVNACHLS CSALLQDNIADAVACAKRVV RDPQGIRAWVAWRNRCQNRD VRQYVQGCGV ; loop_ _Residue_seq_code _Residue_label 1 LYS 2 VAL 3 PHE 4 GLU 5 ARG 6 CYS 7 GLU 8 LEU 9 ALA 10 ARG 11 THR 12 LEU 13 LYS 14 ARG 15 LEU 16 GLY 17 MET 18 ASP 19 GLY 20 TYR 21 ARG 22 GLY 23 ILE 24 SER 25 LEU 26 ALA 27 ASN 28 TRP 29 MET 30 CYS 31 LEU 32 ALA 33 LYS 34 TRP 35 GLU 36 SER 37 GLY 38 TYR 39 ASN 40 THR 41 ARG 42 ALA 43 THR 44 ASN 45 TYR 46 ASN 47 ALA 48 GLY 49 ASP 50 ARG 51 SER 52 THR 53 ASP 54 TYR 55 GLY 56 ILE 57 PHE 58 GLN 59 ILE 60 ASN 61 SER 62 ARG 63 TYR 64 TRP 65 CYS 66 ASN 67 ASP 68 GLY 69 LYS 70 THR 71 PRO 72 GLY 73 ALA 74 VAL 75 ASN 76 ALA 77 CYS 78 HIS 79 LEU 80 SER 81 CYS 82 SER 83 ALA 84 LEU 85 LEU 86 GLN 87 ASP 88 ASN 89 ILE 90 ALA 91 ASP 92 ALA 93 VAL 94 ALA 95 CYS 96 ALA 97 LYS 98 ARG 99 VAL 100 VAL 101 ARG 102 ASP 103 PRO 104 GLN 105 GLY 106 ILE 107 ARG 108 ALA 109 TRP 110 VAL 111 ALA 112 TRP 113 ARG 114 ASN 115 ARG 116 CYS 117 GLN 118 ASN 119 ARG 120 ASP 121 VAL 122 ARG 123 GLN 124 TYR 125 VAL 126 GLN 127 GLY 128 CYS 129 GLY 130 VAL stop_ _Sequence_homology_query_date 2004-07-29 _Sequence_homology_query_revised_last_date 2004-07-16 loop_ _Database_name _Database_accession_code _Database_entry_mol_name _Sequence_query_to_submitted_percentage _Sequence_subject_length _Sequence_identity _Sequence_positive _Sequence_homology_expectation_value PDB 1DI4 "A Chain A, Role Of Amino Acid Residues At TurnsIn The Conformational Stability And Folding Of HumanLysozyme" 101.56 128 98 98 7e-73 PDB 1DI5 "A Chain A, Role Of Amino Acid Residues At TurnsIn The Conformational Stability And Folding Of HumanLysozyme" 100.78 129 99 99 10e-74 PDB 1C43 "A Chain A, Mutant Human Lysozyme With ForeignN-Terminal Residues" 100.00 130 100 100 5e-75 PDB 1C45 "A Chain A, Mutant Human Lysozyme With ForeignN-Terminal Residues" 100.00 130 100 100 5e-75 PDB 1IWT "A Chain A, Crystal Structure Analysis Of HumanLysozyme At 113k." 100.00 130 100 100 1e-75 PDB 1IWU "A Chain A, Crystal Structure Analysis Of HumanLysozyme At 127k." 100.00 130 100 100 1e-75 PDB 1IWV "A Chain A, Crystal Structure Analysis Of HumanLysozyme At 147k." 100.00 130 100 100 1e-75 PDB 1IWW "A Chain A, Crystal Structure Analysis Of HumanLysozyme At 152k." 100.00 130 100 100 1e-75 PDB 1IWX "A Chain A, Crystal Structure Analysis Of HumanLysozyme At 161k." 100.00 130 100 100 1e-75 PDB 1IWY "A Chain A, Crystal Structure Analysis Of HumanLysozyme At 170k." 100.00 130 100 100 1e-75 PDB 1IWZ "A Chain A, Crystal Structure Analysis Of HumanLysozyme At 178k." 100.00 130 100 100 1e-75 PDB 1IY3 "A Chain A, Solution Structure Of The HumanLysozyme At 4 Degree C" 100.00 130 100 100 1e-75 PDB 1IY4 "A Chain A, Solution Structure Of The HumanLysozyme At 35 Degree C" 100.00 130 100 100 1e-75 PDB 1JSF "Full-Matrix Least-Squares Refinement Of HumanLysozyme" 100.00 130 100 100 1e-75 PDB 1JWR "A Chain A, Crystal Structure Of Human LysozymeAt 100 K" 100.00 130 100 100 1e-75 PDB 1LZ1 "Lysozyme (E.C.3.2.1.17)" 100.00 130 100 100 1e-75 PDB 1LZR "Lysozyme (Lz406) (E.C.3.2.1.17) ComplexedWith Tetra-Acetyl-Chitotetraose" 100.00 130 100 100 1e-75 PDB 1LZS "A Chain A, Lysozyme (Lz604) (E.C.3.2.1.17)Complexed With N-Acetylchitose Oligomers" 100.00 130 100 100 1e-75 PDB 1OP9 "B Chain B, Complex Of Human Lysozyme WithCamelid Vhh Hl6 Antibody Fragment" 100.00 130 100 100 1e-75 PDB 1OUF "Contribution Of Hydrophobic Residues To TheStability Of Human Lysozyme: X-Ray Structure Of TheV130a Mutant" 100.00 130 100 100 4e-75 PDB 1RE2 "A Chain A, Human Lysozyme Labelled With Two2',3'-Epoxypropyl Beta- Glycoside Of N-Acetyllactosamine" 100.00 130 100 100 1e-75 PDB 1REM "Human Lysozyme With Man-B1,4-GlcnacCovalently Attached To Asp53" 100.00 130 100 100 1e-75 PDB 1REX "Native Human Lysozyme" 100.00 130 100 100 1e-75 PDB 1REY "Human Lysozyme-N,N'-DiacetylchitobioseComplex" 100.00 130 100 100 1e-75 PDB 1REZ "Human Lysozyme-N-Acetyllactosamine Complex" 100.00 130 100 100 1e-75 PDB 133L "Lysozyme (E.C.3.2.1.17) Mutant With Arg 115Replaced By His (R115h)" 100.00 130 99 99 5e-75 PDB 134L "Lysozyme (E.C.3.2.1.17) Mutant With Arg 115Replaced By Glu (R115e)" 100.00 130 99 99 5e-75 PDB 1B5U "A Chain A, Contribution Of Hydrogen Bonds ToThe Conformational Stability Of Human Lysozyme:Calorimetry And X-Ray Analysis Of Six Ser->ala Mutant" 100.00 130 99 100 3e-75 PDB 1B5V "A Chain A, Contribution Of Hydrogen Bonds ToThe Conformational Stability Of Human Lysozyme:Calorimetry And X-Ray Analysis Of Six Ser->ala Mutants" 100.00 130 99 100 3e-75 PDB 1B5W "A Chain A, Contribution Of Hydrogen Bonds ToThe Conformational Stability Of Human Lysozyme:Calorimetry And X-Ray Analysis Of Six Ser->ala Mutants" 100.00 130 99 100 3e-75 PDB 1B5X "A Chain A, Contribution Of Hydrogen Bonds ToThe Conformational Stability Of Human Lysozyme:Calorimetry And X-Ray Analysis Of Six Ser->ala Mutants" 100.00 130 99 100 3e-75 PDB 1B5Y "A Chain A, Contribution Of Hydrogen Bonds ToThe Conformational Stability Of Human Lysozyme:Calorimetry And X-Ray Analysis Of Six Ser->ala Mutants" 100.00 130 99 100 3e-75 PDB 1B5Z "A Chain A, Contribution Of Hydrogen Bonds ToThe Conformational Stability Of Human Lysozyme:Calorimetry And X-Ray Analysis Of Six Ser->ala Mutants" 100.00 130 99 100 3e-75 PDB 1B7L "A Chain A, Verification Of Spmp Using MutantHuman Lysozymes" 100.00 130 99 99 5e-75 PDB 1B7M "A Chain A, Verification Of Spmp Using MutantHuman Lysozymes" 100.00 130 99 99 5e-75 PDB 1B7N "A Chain A, Verification Of Spmp Using MutantHuman Lysozymes" 100.00 130 99 99 10e-75 PDB 1B7O "A Chain A, Verification Of Spmp Using MutantHuman Lysozymes" 100.00 130 99 99 10e-75 PDB 1B7P "A Chain A, Verification Of Spmp Using MutantHuman Lysozymes" 100.00 130 99 99 2e-74 PDB 1B7Q "A Chain A, Verification Of Spmp Using MutantHuman Lysozymes" 100.00 130 99 99 2e-74 PDB 1B7R "A Chain A, Verification Of Spmp Using MutantHuman Lysozymes" 100.00 130 99 99 9e-75 PDB 1B7S "Verification Of Spmp Using Mutant HumanLysozymes" 100.00 130 99 99 7e-75 PDB 1BB3 "A Chain A, Human Lysozyme Mutant A96l" 100.00 130 99 99 5e-75 PDB 1BB5 "A Chain A, Human Lysozyme Mutant A96l ComplexedWith Chitotriose" 100.00 130 99 99 5e-75 PDB 1CJ6 "A Chain A, T11a Mutant Human Lysozyme" 100.00 130 99 99 5e-75 PDB 1CJ7 "A Chain A, T11v Mutant Human Lysozyme" 100.00 130 99 99 5e-75 PDB 1CJ8 "A Chain A, T40a Mutant Human Lysozyme" 100.00 130 99 99 5e-75 PDB 1CJ9 "A Chain A, T40v Mutant Human Lysozyme" 100.00 130 99 99 5e-75 PDB 1CKC "A Chain A, T43a Mutant Human Lysozyme" 100.00 130 99 99 5e-75 PDB 1CKD "A Chain A, T43v Mutant Human Lysozyme" 100.00 130 99 99 5e-75 PDB 1CKF "A Chain A, T52a Mutant Human Lysozyme" 100.00 130 99 99 5e-75 PDB 1CKG "A Chain A, T52v Mutant Human Lysozyme" 100.00 130 99 99 5e-75 PDB 1CKH "A Chain A, T70v Mutant Human Lysozyme" 100.00 130 99 99 5e-75 PDB 1D6P "A Chain A, Human Lysozyme L63 Mutant LabelledWith 2',3'-Epoxypropyl N, N'-Diacetylchitobiose" 100.00 130 99 99 10e-75 PDB 1D6Q "A Chain A, Human Lysozyme E102 Mutant LabelledWith 2',3'-Epoxypropyl Glycoside Of N-Acetyllactosamine" 100.00 130 99 100 4e-75 PDB 1DI3 "A Chain A, Role Of Amino Acid Residues At TurnsIn The Conformational Stability And Folding Of HumanLysozyme" 100.00 130 99 99 9e-75 PDB 1EQ4 "A Chain A, Crystal Structures Of Salt BridgeMutants Of Human Lysozyme" 100.00 130 99 100 3e-75 PDB 1EQ5 "A Chain A, Crystal Structures Of Salt BridgeMutants Of Human Lysozyme" 100.00 130 99 100 5e-75 PDB 1EQE "A Chain A, Crystal Structures Of Salt BridgeMutants Of Human Lysozyme" 100.00 130 99 100 5e-75 PDB 1GAY "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 9e-75 PDB 1GAZ "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 100 2e-75 PDB 1GB0 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 100 3e-75 PDB 1GB2 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 100 3e-75 PDB 1GB3 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 5e-75 PDB 1GB5 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 9e-75 PDB 1GB6 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 100 2e-75 PDB 1GB7 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 100 3e-75 PDB 1GB8 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 100 3e-75 PDB 1GB9 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 5e-75 PDB 1GBO "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 9e-75 PDB 1GBW "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 100 2e-75 PDB 1GBX "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 100 3e-75 PDB 1GBY "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 100 3e-75 PDB 1GBZ "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 5e-75 PDB 1GDW "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At Left-Handed Helical Positions" 100.00 130 99 99 9e-75 PDB 1GDX "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At Left-Handed Helical Positions" 100.00 130 99 99 7e-75 PDB 1GE0 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At Left-Handed Helical Positions" 100.00 130 99 99 2e-74 PDB 1GE1 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At Left-Handed Helical Positions" 100.00 130 99 99 7e-75 PDB 1GE2 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At Left-Handed Helical Positions" 100.00 130 99 99 2e-74 PDB 1GE3 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At Left-Handed Helical Positions" 100.00 130 99 99 7e-75 PDB 1GE4 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At Left-Handed Helical Positions" 100.00 130 99 99 10e-75 PDB 1GEV "A Chain A, Buried Polar Mutant Human Lysozyme" 100.00 130 99 99 5e-75 PDB 1GEZ "A Chain A, Buried Polar Mutant Human Lysozyme" 100.00 130 99 100 3e-75 PDB 1GF0 "A Chain A, Buried Polar Mutant Human Lysozyme" 100.00 130 99 100 3e-75 PDB 1GF3 "A Chain A, Buried Polar Mutant Human Lysozyme" 100.00 130 99 100 3e-75 PDB 1GF4 "A Chain A, Buried Polar Mutant Human Lysozyme" 100.00 130 99 99 4e-75 PDB 1GF5 "A Chain A, Buried Polar Mutant Human Lysozyme" 100.00 130 99 100 3e-75 PDB 1GF6 "A Chain A, Buried Polar Mutant Human Lysozyme" 100.00 130 99 99 4e-75 PDB 1GF7 "A Chain A, Buried Polar Mutant Human Lysozyme" 100.00 130 99 99 4e-75 PDB 1GF8 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 7e-75 PDB 1GF9 "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 5e-75 PDB 1GFA "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 9e-75 PDB 1GFE "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 9e-75 PDB 1GFG "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 9e-75 PDB 1GFH "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 5e-75 PDB 1GFJ "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 9e-75 PDB 1GFK "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 9e-75 PDB 1GFR "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 9e-75 PDB 1GFT "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 5e-75 PDB 1GFU "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 9e-75 PDB 1GFV "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 9e-75 PDB 1HNL "Lysozyme (E.C.3.2.1.17) Mutant With Cys 77Replaced By Ala (C77a) Complexed With Glutathione" 100.00 130 99 99 2e-74 PDB 1I1Z "A Chain A, Mutant Human Lysozyme (Q86d)" 100.00 130 99 99 5e-75 PDB 1I20 "A Chain A, Mutant Human Lysozyme (A92d)" 100.00 130 99 99 7e-75 PDB 1INU "A Chain A, Crystal Structure Of Mutant HumanLysozyme Substituted At The Surface Positions" 100.00 130 99 99 9e-75 PDB 1IP1 "A Chain A, G37a Human Lysozyme" 100.00 130 99 99 7e-75 PDB 1IP2 "A Chain A, G48a Human Lysozyme" 100.00 130 99 99 7e-75 PDB 1IP3 "A Chain A, G68a Human Lysozyme" 100.00 130 99 99 7e-75 PDB 1IP4 "A Chain A, G72a Human Lysozyme" 100.00 130 99 99 7e-75 PDB 1IP5 "A Chain A, G105a Human Lysozyme" 100.00 130 99 99 7e-75 PDB 1IP6 "A Chain A, G127a Human Lysozyme" 100.00 130 99 99 7e-75 PDB 1IP7 "A Chain A, G129a Human Lysozyme" 100.00 130 99 99 7e-75 PDB 1JKA "Human Lysozyme Mutant With Glu 35 Replaced ByAsp" 100.00 130 99 100 3e-75 PDB 1JKB "Human Lysozyme Mutant With Glu 35 Replaced ByAla" 100.00 130 99 99 7e-75 PDB 1JKC "Human Lysozyme Mutant With Trp 109 ReplacedBy Phe" 100.00 130 99 100 2e-74 PDB 1JKD "Human Lysozyme Mutant With Trp 109 ReplacedBy Ala" 100.00 130 99 99 6e-74 PDB 1LAA "Lysozyme (E.C.3.2.1.17) Mutant With Asp 53Replaced By Glu (D53E)" 100.00 130 99 100 4e-75 PDB 1LHH "Lysozyme (E.C.3.2.1.17) Mutant With Val 110Replaced By Pro (V110p)" 100.00 130 99 99 7e-75 PDB 1LHI "Lysozyme (E.C.3.2.1.17) Mutant With Pro 71Replaced By Gly (P71g)" 100.00 130 99 99 2e-74 PDB 1LHJ "Lysozyme (E.C.3.2.1.17) Mutant With Pro 103Replaced By Gly (P103g)" 100.00 130 99 99 2e-74 PDB 1LHK "Lysozyme (E.C.3.2.1.17) Mutant With Asp 91Replaced By Pro (D91p)" 100.00 130 99 99 9e-75 PDB 1LHL "Lysozyme (E.C.3.2.1.17) Mutant With Ala 47Replaced By Proline (A47p)" 100.00 130 99 99 5e-75 PDB 1LOZ "Amyloidogenic Variant (I56t) Variant Of HumanLysozyme" 100.00 130 99 99 5e-75 PDB 1LYY "Amyloidogenic Variant (Asp67his) Of HumanLysozyme" 100.00 130 99 99 9e-75 PDB 1LZ4 "Lysozyme (E.C.3.2.1.17) Mutant With Cys 77Replaced By Ala (C77a)" 100.00 130 99 99 2e-74 PDB 1OUA "Contribution Of Hydrophobic Residues To TheStability Of Human Lysozyme: X-Ray Structure Of The I56tMutant" 100.00 130 99 99 5e-75 PDB 1OUB "Contribution Of Hydrophobic Residues To TheStability Of Human Lysozyme: X-Ray Structure Of TheV100a Mutant" 100.00 130 99 99 4e-75 PDB 1OUC "Contribution Of Hydrophobic Residues To TheStability Of Human Lysozyme: X-Ray Structure Of TheV110a Mutant" 100.00 130 99 99 4e-75 PDB 1OUD "Contribution Of Hydrophobic Residues To TheStability Of Human Lysozyme: X-Ray Structure Of TheV121a Mutant" 100.00 130 99 99 4e-75 PDB 1OUE "Contribution Of Hydrophobic Residues To TheStability Of Human Lysozyme: X-Ray Structure Of TheV125a Mutant" 100.00 130 99 99 4e-75 PDB 1OUG "Contribution Of Hydrophobic Residues To TheStability Of Human Lysozyme: X-Ray Structure Of The V2aMutant" 100.00 130 99 99 4e-75 PDB 1OUH "Contribution Of Hydrophobic Residues To TheStability Of Human Lysozyme: X-Ray Structure Of The V74aMutant" 100.00 130 99 99 4e-75 PDB 1OUI "Contribution Of Hydrophobic Residues To TheStability Of Human Lysozyme: X-Ray Structure Of The V93aMutant" 100.00 130 99 99 4e-75 PDB 1OUJ "Contribution Of Hydrophobic Residues To TheStability Of Human Lysozyme: X-Ray Structure Of The V99aMutant" 100.00 130 99 99 4e-75 PDB 1TAY "Lysozyme (E.C.3.2.1.17) Mutant With Tyr 63Replaced By Ala (Y63A)" 100.00 130 99 99 2e-74 PDB 1TBY "Lysozyme (E.C.3.2.1.17) Mutant With Tyr 63Replaced By Leu (Y63L)" 100.00 130 99 99 10e-75 PDB 1TCY "Lysozyme (E.C.3.2.1.17) Mutant With Tyr 63Replaced By Phe (Y63F)" 100.00 130 99 100 4e-75 PDB 1TDY "Lysozyme (E.C.3.2.1.17) Mutant With Tyr 63Replaced By Trp (Y63W)" 100.00 130 99 100 5e-75 PDB 1UBZ "A Chain A, Crystal Structure Of Glu102-MutantHuman Lysozyme Doubly Labeled With 2',3'-EpoxypropylBeta-Glycoside Of N- Acetyllactosamine" 100.00 130 99 100 4e-75 PDB 1WQM "Contribution Of Hydrogen Bonds To TheConformational Stability Of Human Lysozyme" 100.00 130 99 100 4e-75 PDB 1WQN "Contribution Of Hydrogen Bonds To TheConformational Stability Of Human Lysozyme" 100.00 130 99 100 4e-75 PDB 1WQO "Contribution Of Hydrogen Bonds To TheConformational Stability Of Human Lysozyme" 100.00 130 99 100 4e-75 PDB 1WQP "Contribution Of Hydrogen Bonds To TheConformational Stability Of Human Lysozyme" 100.00 130 99 100 4e-75 PDB 1WQQ "Contribution Of Hydrogen Bonds To TheConformational Stability Of Human Lysozyme" 100.00 130 99 100 4e-75 PDB 1WQR "Contribution Of Hydrogen Bonds To TheConformational Stability Of Human Lysozyme" 100.00 130 99 100 4e-75 PDB 1YAM "Mol_id: 1; Molecule: Lysozyme; Chain: Null;Ec: 3.2.1.17; Engineered: Yes; Mutation: I106v" 100.00 130 99 100 2e-75 PDB 1YAN "Mol_id: 1; Molecule: Lysozyme; Chain: Null;Ec: 3.2.1.17; Engineered: Yes; Mutation: I23v" 100.00 130 99 100 2e-75 PDB 1YAO "Mol_id: 1; Molecule: Lysozyme; Chain: Null;Ec: 3.2.1.17; Engineered: Yes; Mutation: I56v" 100.00 130 99 100 2e-75 PDB 1YAP "Mol_id: 1; Molecule: Lysozyme; Chain: Null;Ec: 3.2.1.17; Engineered: Yes; Mutation: I59v" 100.00 130 99 100 2e-75 PDB 1YAQ "Mol_id: 1; Molecule: Lysozyme; Chain: Null;Ec: 3.2.1.17; Engineered: Yes; Mutation: I89v" 100.00 130 99 100 2e-75 PDB 207L "A Chain A, Mutant Human Lysozyme C77a" 100.00 130 99 99 2e-74 PDB 208L "A Chain A, Mutant Human Lysozyme C77a" 100.00 130 99 99 2e-74 PDB 2HEA "Contribution Of Water Molecules In TheInterior Of A Protein To The Conformational Stability" 100.00 130 99 99 5e-75 PDB 2HEB "Contribution Of Water Molecules In TheInterior Of A Protein To The Conformational Stability" 100.00 130 99 99 5e-75 PDB 2HEC "Contribution Of Water Molecules In TheInterior Of A Protein To The Conformational Stability" 100.00 130 99 99 5e-75 PDB 2HED "Contribution Of Water Molecules In TheInterior Of A Protein To The Conformational Stability" 100.00 130 99 99 5e-75 PDB 2HEE "Contribution Of Water Molecules In TheInterior Of A Protein To The Conformational Stability" 100.00 130 99 99 10e-75 PDB 2HEF "Contribution Of Water Molecules In TheInterior Of A Protein To The Conformational Stability" 100.00 130 99 99 5e-75 PDB 2MEA "A Chain A, Changes In Conformational StabilityOf A Series Of Mutant Human Lysozymes At ConstantPositions" 100.00 130 99 99 4e-75 PDB 2MEB "Changes In Conformational Stability Of ASeries Of Mutant Human Lysozymes At Constant Positions" 100.00 130 99 100 2e-75 PDB 2MEC "A Chain A, Changes In Conformational StabilityOf A Series Of Mutant Human Lysozymes At ConstantPositions" 100.00 130 99 100 3e-75 PDB 2MED "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 99 99 4e-75 PDB 2MEE "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 99 100 2e-75 PDB 2MEF "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 99 100 3e-75 PDB 2MEG "Changes In Conformational Stability Of ASeries Of Mutant Human Lysozymes At Constant Positions" 100.00 130 99 99 7e-75 PDB 2MEH "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 99 99 5e-75 PDB 2MEI "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 99 99 5e-75 PDB 1BB4 "A Chain A, Human Lysozyme Double Mutant A96l,W109h" 100.00 130 98 98 2e-73 PDB 1LHM "Lysozyme (E.C.3.2.1.17) (Mutant With Cys 77Replaced By Ala And Cys 95 Replaced By Ala) (C77A,C95A)" 100.00 130 98 98 2e-73 PDB 1QSW "A Chain A, Crystal Structure Analysis Of AHuman Lysozyme Mutant W64c C65a" 100.00 130 98 98 5e-73 PDB 2BQA "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 2e-73 PDB 2BQK "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 5e-73 PDB 2LHM "Lysozyme (E.C.3.2.1.17) (Apo) (Mutant With Gln86 Replaced B Asp And Ala 92 Replaced By Asp)(Q86D,A92D)" 100.00 130 98 98 3e-74 PDB 3LHM "Lysozyme (E.C.3.2.1.17) (Holo) (Mutant WithGln 86 Replaced By Asp And Ala 92 Replaced By Asp)(Q86D,A92D)" 100.00 130 98 98 3e-74 PDB 1I22 "A Chain A, Mutant Human Lysozyme(A83kQ86DA92D)" 100.00 130 98 98 10e-74 PDB 1IX0 "A Chain A, I59a-3ss Human Lysozyme" 100.00 130 98 98 7e-73 PDB 2BQB "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 2e-73 PDB 2BQC "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 2e-73 PDB 2BQD "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 2e-73 PDB 2BQE "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 2e-73 PDB 2BQF "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 2e-73 PDB 2BQG "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 5e-73 PDB 2BQH "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 5e-73 PDB 2BQI "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 5e-73 PDB 2BQJ "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 5e-73 PDB 2BQL "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 5e-73 PDB 2BQM "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 5e-73 PDB 2BQN "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 5e-73 PDB 2BQO "Contribution Of Hydrophobic Effect To TheConformational Stability Of Human Lysozyme" 100.00 130 98 98 5e-73 PDB 1C46 "A Chain A, Mutant Human Lysozyme With ForeignN-Terminal Residues" 99.24 131 100 100 1e-75 PDB 1C7P "A Chain A, Crystal Structure Of Mutant HumanLysozyme With Four Extra Residues (Eaea) At TheN-Terminal" 97.01 134 100 100 1e-75 PDB 1IOC "A Chain A, Crystal Structure Of Mutant HumanLysozyme, Eaea-I56t" 97.01 134 99 99 5e-75 DBJ BAA00314.1 "lysozyme [synthetic construct]" 99.24 131 99 99 10e-75 EMBL CAA32175.1 "lysozyme [Homo sapiens]" 100.00 130 100 100 1e-75 EMBL CAA53144.1 "lysozyme [synthetic construct]" 99.24 131 100 100 1e-75 GenBank AAA59535.1 "lysozyme precursor (EC 3.2.1.17)" 87.84 148 100 100 1e-75 GenBank AAA59536.1 "lysozyme precursor (EC 3.2.1.17)" 87.84 148 100 100 1e-75 GenBank AAB41205.1 "lysozyme c precursor [Gorilla gorilla]" 87.84 148 100 100 1e-75 GenBank AAB41209.1 "lysozyme c precursor [Pan troglodytes]" 87.84 148 100 100 1e-75 GenBank AAB41214.1 "lysozyme c precursor [Pan paniscus]" 87.84 148 100 100 1e-75 PIR LZHU "lysozyme (EC 3.2.1.17) c precursor [validated]- human" 87.84 148 100 100 1e-75 REF NP_000230.1 "lysozyme precursor [Homo sapiens]" 87.84 148 100 100 1e-75 SWISS-PROT P61626 "LYC_HUMAN Lysozyme C precursor(1,4-beta-N-acetylmuramidase C)" 87.84 148 100 100 1e-75 SWISS-PROT P61628 "LYC_PANTR Lysozyme C precursor(1,4-beta-N-acetylmuramidase C)" 87.84 148 100 100 1e-75 SWISS-PROT P79179 "LYC_GORGO Lysozyme C precursor(1,4-beta-N-acetylmuramidase C)" 87.84 148 100 100 1e-75 SWISS-PROT P79239 "LYC_PONPY Lysozyme C precursor(1,4-beta-N-acetylmuramidase C)" 87.84 148 99 99 5e-75 stop_ save_ #################### # Natural source # #################### save_natural_source _Saveframe_category natural_source loop_ _Mol_label _Organism_name_common _NCBI_taxonomy_ID _Genus _Species ? ? ? ? ? stop_ save_ ######################### # Experimental source # ######################### save_experimental_source _Saveframe_category experimental_source loop_ _Mol_label _Production_method $lysozyme 'not available' stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample_one _Saveframe_category sample _Sample_type solution loop_ _Mol_label _Concentration_value _Concentration_value_units _Isotopic_labeling ? ? ? ? stop_ save_ ####################### # Sample conditions # ####################### save_sample_condition_set_one _Saveframe_category sample_conditions loop_ _Variable_type _Variable_value _Variable_value_error _Variable_value_units pH 4 . na temperature 313 . K stop_ save_ #################### # NMR parameters # #################### ############################## # Assigned chemical shifts # ############################## ################################ # Chemical shift referencing # ################################ save_chem_shift_reference_par_set_one _Saveframe_category chemical_shift_reference loop_ _Mol_common_name _Atom_type _Chem_shift_units _Chem_shift_value 'liquid NH3' N ppm 0 stop_ save_ ################################### # Assigned chemical shift lists # ################################### ################################################################### # Chemical Shift Ambiguity Index Value Definitions # # # # Index Value Definition # # # # 1 Unique # # 2 Ambiguity of geminal atoms or geminal methyl # # proton groups # # 3 Aromatic atoms on opposite sides of the ring # # (e.g. Tyr HE1 and HE2 protons) # # 4 Intraresidue ambiguities (e.g. Lys HG and # # HD protons) # # 5 Interresidue ambiguities (Lys 12 vs. Lys 27) # # 9 Ambiguous, specific ambiguity not defined # # # ################################################################### save_chemical_shift_assignment_data_set_one _Saveframe_category assigned_chemical_shifts loop_ _Sample_label $sample_one stop_ _Sample_conditions_label $sample_condition_set_one _Chem_shift_reference_set_label $chem_shift_reference_par_set_one _Mol_system_component_name 'lysozyme' loop_ _Atom_shift_assign_ID _Residue_seq_code _Residue_label _Atom_name _Atom_type _Chem_shift_value _Chem_shift_value_error _Chem_shift_ambiguity_code 1 2 VAL N N 126.78 . 1 2 3 PHE N N 127.38 . 1 3 4 GLU N N 120.08 . 1 4 5 ARG N N 125.58 . 1 5 6 CYS N N 114.28 . 1 6 7 GLU N N 123.48 . 1 7 8 LEU N N 121.78 . 1 8 9 ALA N N 123.68 . 1 9 10 ARG N N 115.08 . 1 10 11 THR N N 118.48 . 1 11 12 LEU N N 119.08 . 1 12 13 LYS N N 119.28 . 1 13 14 ARG N N 121.48 . 1 14 15 LEU N N 116.98 . 1 15 16 GLY N N 106.28 . 1 16 17 MET N N 114.08 . 1 17 18 ASP N N 118.28 . 1 18 19 GLY N N 119.08 . 1 19 20 TYR N N 126.08 . 1 20 21 ARG N N 125.78 . 1 21 22 GLY N N 103.18 . 1 22 23 ILE N N 124.28 . 1 23 24 SER N N 122.88 . 1 24 25 LEU N N 121.78 . 1 25 26 ALA N N 118.48 . 1 26 27 ASN ND2 N 116.70 . 1 27 27 ASN N N 116.78 . 1 28 28 TRP NE1 N 130.80 . 1 29 28 TRP N N 119.98 . 1 30 29 MET N N 116.38 . 1 31 30 CYS N N 119.68 . 1 32 31 LEU N N 118.58 . 1 33 32 ALA N N 119.08 . 1 34 33 LYS N N 119.78 . 1 35 34 TRP NE1 N 129.20 . 1 36 34 TRP N N 117.78 . 1 37 35 GLU N N 116.18 . 1 38 36 SER N N 107.88 . 1 39 37 GLY N N 115.98 . 1 40 38 TYR N N 108.48 . 1 41 39 ASN ND2 N 113.50 . 1 42 39 ASN N N 117.28 . 1 43 40 THR N N 115.28 . 1 44 41 ARG N N 111.78 . 1 45 42 ALA N N 122.58 . 1 46 43 THR N N 113.88 . 1 47 44 ASN ND2 N 116.80 . 1 48 44 ASN N N 119.18 . 1 49 45 TYR N N 127.28 . 1 50 46 ASN ND2 N 116.10 . 1 51 46 ASN N N 127.98 . 1 52 47 ALA N N 125.48 . 1 53 48 GLY N N 104.08 . 1 54 49 ASP N N 116.78 . 1 55 50 ARG N N 114.28 . 1 56 51 SER N N 113.58 . 1 57 52 THR N N 116.18 . 1 58 53 ASP N N 124.38 . 1 59 54 TYR N N 118.38 . 1 60 55 GLY N N 112.28 . 1 61 56 ILE N N 121.58 . 1 62 57 PHE N N 115.28 . 1 63 58 GLN NE2 N 117.80 . 1 64 58 GLN N N 113.88 . 1 65 59 ILE N N 121.98 . 1 66 60 ASN ND2 N 117.80 . 1 67 60 ASN N N 127.58 . 1 68 61 SER N N 119.28 . 1 69 62 ARG N N 123.68 . 1 70 63 TYR N N 114.18 . 1 71 64 TRP NE1 N 130.30 . 1 72 64 TRP N N 114.58 . 1 73 65 CYS N N 111.08 . 1 74 66 ASN ND2 N 115.30 . 1 75 66 ASN N N 119.28 . 1 76 67 ASP N N 131.08 . 1 77 68 GLY N N 108.58 . 1 78 69 LYS N N 117.68 . 1 80 72 GLY N N 110.18 . 1 81 73 ALA N N 110.78 . 1 82 74 VAL N N 120.38 . 1 83 75 ASN ND2 N 107.50 . 1 84 75 ASN N N 118.58 . 1 85 76 ALA N N 120.48 . 1 86 77 CYS N N 110.68 . 1 87 78 HIS N N 117.48 . 1 88 79 LEU N N 118.08 . 1 89 80 SER N N 117.28 . 1 90 81 CYS N N 125.68 . 1 91 82 SER N N 114.38 . 1 92 83 ALA N N 125.68 . 1 93 84 LEU N N 116.38 . 1 94 85 LEU N N 117.48 . 1 95 86 GLN NE2 N 115.10 . 1 96 86 GLN N N 116.28 . 1 97 87 ASP N N 119.98 . 1 98 88 ASN ND2 N 114.30 . 1 99 88 ASN N N 114.38 . 1 100 89 ILE N N 118.08 . 1 101 90 ALA N N 125.88 . 1 102 91 ASP N N 118.08 . 1 103 92 ALA N N 122.98 . 1 104 93 VAL N N 118.08 . 1 105 94 ALA N N 121.38 . 1 106 95 CYS N N 115.48 . 1 107 96 ALA N N 124.18 . 1 108 97 LYS N N 114.18 . 1 109 98 ARG N N 118.28 . 1 110 99 VAL N N 123.08 . 1 111 100 VAL N N 108.48 . 1 112 101 ARG N N 117.18 . 1 114 104 GLN NE2 N 113.40 . 1 115 104 GLN N N 113.88 . 1 116 105 GLY N N 108.68 . 1 117 106 ILE N N 126.08 . 1 118 107 ARG N N 116.78 . 1 119 108 ALA N N 120.08 . 1 120 109 TRP NE1 N 132.40 . 1 121 109 TRP N N 116.48 . 1 122 110 VAL N N 123.98 . 1 123 111 ALA N N 119.98 . 1 124 112 TRP NE1 N 130.60 . 1 125 112 TRP N N 114.78 . 1 126 113 ARG N N 118.68 . 1 127 114 ASN ND2 N 113.30 . 1 128 114 ASN N N 111.68 . 1 129 115 ARG N N 113.88 . 1 130 116 CYS N N 114.38 . 1 131 117 GLN NE2 N 111.50 . 1 132 117 GLN N N 120.68 . 1 133 118 ASN ND2 N 114.90 . 1 134 118 ASN N N 119.28 . 1 135 119 ARG N N 116.58 . 1 136 120 ASP N N 119.18 . 1 137 121 VAL N N 118.48 . 1 138 122 ARG N N 123.48 . 1 139 123 GLN NE2 N 113.50 . 1 140 123 GLN N N 115.88 . 1 141 124 TYR N N 116.48 . 1 142 125 VAL N N 104.78 . 1 143 126 GLN NE2 N 113.30 . 1 144 126 GLN N N 124.38 . 1 145 127 GLY N N 113.38 . 1 146 128 CYS N N 114.18 . 1 147 129 GLY N N 111.48 . 1 stop_ save_